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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-NCC-149
NCC-149

Chemical Structure : NCC-149

CAS No.: 1316652-41-1

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NCC-149 (NCC 149, NCC149)

货号: PC-60134Not For Human Use, Lab Use Only.

NCC-149 (NCC149, NCC 149) is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.

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5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NCC-149 (NCC149, NCC 149) is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.
NCC-149 displays high selectivity over major HDACs (HDAC1: IC50 38 uM, HDAC2 >100 uM, HDAC4: IC50: 44 uM,HDAC6: IC50 2.4 uM).

物理化学性质&存储条件

分子量 326.374
分子式 C16H14N4O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-hydroxy-3-(1-((phenylthio)methyl)-1H-1,2,3-triazol-4-yl)benzamide

参考文献

1. Suzuki T, et al. ChemMedChem. 2014 Mar;9(3):657-64.

2. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.

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