HDAC6 inhibitor 7b

Chemical Structure : HDAC6 inhibitor 7b

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货号: PC-27055Not For Human Use, Lab Use Only.

HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively.

物理化学性质&存储条件

分子量	357.41
分子式	C19H23N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-Hydroxy-4-[[1-(4-hydroxybutyl)-3-phenylureido]methyl]benzamide

参考文献

1. Tavares MT, et al. ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036.

2. Losson H, et al. Pharmacol Res. 2020 Oct;160:105058.