| Cat. No. |
Product Name |
Information |
| PC-45490 |
UMI-77
Mcl-1 inhibitor
|
UMI-77 is a potent and selective Mcl-1 inhibitor with Ki of 0.49 uM. |
| PC-45314 |
Gossypol acetic acid
BCL-2 inhibitor
|
Gossypol acetic acid ((±)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes. |
| PC-44439 |
AT-101
BCL-2 inhibitor
|
AT-101 ((R)-(-)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes. |
| PC-43513 |
Gossypol
BCL-2 inhibitor
|
Gossypol (BL-193) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes. |
| PC-42244 |
S63845
Mcl-1 inhibitor
|
S63845 is a highly potent, selective Mcl-1 inhibitor with Kd of 0.19 nM, with no appreciable binding affinity to BCL-2 or BCL-XL (Ki>10 uM). |
| PC-47486 |
Bax inhibitor peptide V5
Bax inhibitor
|
Bax inhibitor peptide V5 (Val-Pro-Met-Leu-Lys, BIP-V5) is cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |
| PC-45901 |
ABT-737
BCL-2 inhibitor
|
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively. |
| PC-25072 |
Mesutoclax
BCL-2 inhibitor
|
Mesutoclax (ICP-248) is a highly selective and potent, orally active BCL2 inhibitor. |
| PC-25038 |
Dalvotoclax
BCL-2 inhibitor
|
Dalvotoclax is a potent, selective inhibitor of anti-apoptotic protein Bcl-2. |
| PC-24935 |
Asaretoclax
BCL-2 inhibitor
|
Asaretoclax (ZN-d5) is a potent, selective and orally bioavailable inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities. |
| PC-24442 |
Foselutoclax
BCL-xL inhibitor
|
Foselutoclax (UBX1325) is a senolytic small-molecule inhibitor of BCL-xL. |
| PC-24290 |
WEHI-3773
VDAC2-BAX inhibitor
|
WEHI-3773 is a small molecule inhibitor of interaction between VDAC2 and BAX, inhibits apoptosis mediated by BAX by blocking VDAC2-mediated BAX recruitment to mitochondria. |
