Gossypol |CAS:303-45-7 Probechem Biochemicals

Chemical Structure : Gossypol

CAS No.: 303-45-7

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Gossypol (BL-193)

货号: PC-43513Not For Human Use, Lab Use Only.

Gossypol (BL-193) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.

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100 mg	￥1180	In stock
200 mg	￥1780	In stock
500 mg		Get quote
1 g		Get quote

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生物&药学活性

Gossypol (BL-193) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
Gossypol (BL-193) is a BH3 mimetic that binds and antagonizes anti-apoptotic effect of Bcl-2 family proteins, inhibits tumor growth in Wus1-bearing mice.

物理化学性质&存储条件

分子量	518.5544
分子式	C30H30O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-

参考文献

1. Lin J, et al. Oncol Rep. 2013 Aug;30(2):731-8.

2. Ciereszko A, et al. Aquat Toxicol. 2000,49(3):181-187.

3. Ferdek PE, et al. Cell Death Dis. 2017 Mar 2;8(3):e2640.

Gossypol (BL-193)

生物&药学活性

物理化学性质&存储条件

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Gossypol (BL-193)

生物&药学活性

物理化学性质&存储条件

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