AT-101 |CAS:866541-93-7 Probechem Biochemicals

Chemical Structure : AT-101

CAS No.: 866541-93-7

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AT-101 ((R)-(-)-Gossypol acetic acid;(-)-Gossypol acetic acid)

货号: PC-44439Not For Human Use, Lab Use Only.

AT-101 ((R)-(-)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.

规格	价格	库存
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

AT-101 ((R)-(-)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
AT-101 a BH3 mimetic that binds and antagonizes anti-apoptotic effect of Bcl-2 family proteins, inhibits tumor growth in Wus1-bearing mice.

物理化学性质&存储条件

分子量	578.6064
分子式	C32H34O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO; Methanol: 7.75 mg/mL
Chemical Name/SMILES	[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-, (2R)-, compd. with acetic acid (1:1)

参考文献

1. Lin J, et al. Oncol Rep. 2013 Aug;30(2):731-8.

2. Ciereszko A, et al. Aquat Toxicol. 2000,49(3):181-187.

3. Ferdek PE, et al. Cell Death Dis. 2017 Mar 2;8(3):e2640.

AT-101 ((R)-(-)-Gossypol acetic acid;(-)-Gossypol acetic acid)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

AT-101 ((R)-(-)-Gossypol acetic acid;(-)-Gossypol acetic acid)

生物&药学活性

物理化学性质&存储条件

参考文献

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