Gossypol acetic acid |CAS:12542-36-8 Probechem Biochemicals

Chemical Structure : Gossypol acetic acid

CAS No.: 12542-36-8

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Gossypol acetic acid ((±)-Gossypol acetic acid)

货号: PC-45314Not For Human Use, Lab Use Only.

Gossypol acetic acid ((±)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.

规格	价格	库存
100 mg	￥1280	In stock
200 mg	￥1880	In stock
500 mg		Get quote
1 g		Get quote

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生物&药学活性

Gossypol acetic acid ((±)-Gossypol acetic acid) is a natural phenol that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
Gossypol acetic acid is a BH3 mimetic that binds and antagonizes anti-apoptotic effect of Bcl-2 family proteins, inhibits tumor growth in Wus1-bearing mice.

物理化学性质&存储条件

分子量	578.6064
分子式	C32H34O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarbaldehyde,acetic acid

参考文献

1. Lin J, et al. Oncol Rep. 2013 Aug;30(2):731-8.

2. Ciereszko A, et al. Aquat Toxicol, 2000,49(3):181-187.

3. Ferdek PE, et al. Cell Death Dis. 2017 Mar 2;8(3):e2640.

Gossypol acetic acid ((±)-Gossypol acetic acid)

生物&药学活性

物理化学性质&存储条件

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Gossypol acetic acid ((±)-Gossypol acetic acid)

生物&药学活性

物理化学性质&存储条件

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