| Cat. No. |
Product Name |
Information |
| PC-60194 |
AnCoA4
Orai1 channel inhibitor
|
AnCoA4 (AnCoA-4, Jamaicin) is a potent Orai1 channel inhibitor that inhibits store-operated calcium (SOC) with EC50 of 0.88 uM. |
| PC-60005 |
A-317567
|
A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM. |
| PC-47508 |
Benzocaine
Sodium channel inhibitor
|
Benzocaine is a local anesthetic, inhibits voltage-dependent sodium channels (VDSCs) on the neuron membrane, stopping the propagation of the action potential. |
| PC-45927 |
Proparacaine hydrochloride
Sodium channel inhibitor
|
Proparacaine hydrochloride (Proxymetacaine hydrochloride) is an irreversible local anesthetic, inhibits pain sensations that is believed to act as an antagonist on voltage-gated sodium channels. |
| PC-45625 |
Nav1.7-IN-2
NaV1.7 inhibitor
|
Nav1.7-IN-2 is a potent, selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50=80 nM), extracts from patent WO/2011103196 A1, compound example J. |
| PC-45224 |
Ranolazine dihydrochloride
Sodium channel inhibitor
|
Ranolazine dihydrochloride is an anti-ischemic agent that has been shown to inhibit late I(Na) and I(Kr) and to have antiarrhythmic effects in various preclinical in vitro models. |
| PC-42318 |
ETH2120
Sodium ionophore
|
ETH2120 is a sodium ionophore, relieves hydrogen-dependent caffeate reduction and completely abolishes ATP synthesis in cells. |
| PC-42201 |
Nicainoprol
Sodium channels inhibitor
|
A sodium channels blocker, adrenergic receptor antagonist and class 1 antiarrhythmic agent.. |
| PC-45079 |
ICA-121431
Nav1.3/Nav1.1 inhibitor
|
A potent, selective small molecule human Nav1.3/Nav1.1 channel inhibitor with IC50 of 19 nM. |
| PC-45762 |
XEN-907
NaV1.7 inhibitor
|
XEN-907 (XEN907) is a potent, selective NaV1.7 blocker with IC50 of 3 nM. |
| PC-42804 |
A-803467
Nav1.8 inhibitor
|
A-803467 (A803467) potent and selective Nav1.8 sodium channel blocker with IC50 of 8 nM. |
| PC-45068 |
Eleclazine hydrochloride
Sodium current inhibitor
|
A novel, potent, and selective inhibitor of Late sodium current (late INa) for treatment of long QT-3 syndrome (LQT-3), hypertrophic cardiomyopathy (HCM), and ventricular tachycardia–ventricular fibrillation (VT–VF). |
