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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-PF-04531083
PF-04531083

Chemical Structure : PF-04531083

CAS No.: 1079400-07-9

PF-04531083 (PF-4531083, PF 04531083)

货号: PC-61870Not For Human Use, Lab Use Only.

PF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.

物理化学性质&存储条件

分子量 357.798
分子式 C17H16ClN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide

参考文献

1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.

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