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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-PF-05241328
PF-05241328

Chemical Structure : PF-05241328

CAS No.: 1387633-03-5

PF-05241328 (PF05241328;PF 5241328)

货号: PC-61857Not For Human Use, Lab Use Only.

PF-05241328 (PF 5241328) is a potent and selective, orally active inhibitor of voltage-dependent sodium channel Nav1.7 with IC50 of 31 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PF-05241328 (PF 5241328) is a potent and selective, orally active inhibitor of voltage-dependent sodium channel Nav1.7 with IC50 of 31 nM.

物理化学性质&存储条件

分子量 436.911
分子式 C19H21ClN4O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(5-Chloro-6-(2-methylpropoxy)-3-pyridinyl)-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide

参考文献

1. Jones HM, et al. Clin Pharmacokinet. 2016 Jul;55(7):875-87.

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