| Cat. No. |
Product Name |
Information |
| PC-44660 |
NSC 23766
Rac inhibitor
|
NSC 23766 (NSC23766) is a specific small molecule inhibitor of Rac GTPase.
|
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-23016 |
DU102
Arf1 inhibitor
|
DU102 is a potent small molecule inhibitor of small G protein Arf1, binds to the catalytic pocket of the Arf1-GDP-Sec7, inhibit Arf1 activity by binding to Arf1 and Arf-GEF. |
| PC-23015 |
DU101
Arf1 inhibitor
|
DU101 is a potent small molecule inhibitor of small G protein Arf1, binds to the catalytic pocket of the Arf1-GDP-Sec7, inhibit Arf1 activity by binding to Arf1 and Arf-GEF. |
| PC-22522 |
ARN25062
Cdc42 inhibitor
|
ARN25062 is a potent, selective inhibitor of CDC42 GTPases (CDC42, RHOJ, RHOQ), exhibits s antiproliferative activity of melanoma cancer cell lines that have a BRAFV600E mutation (SKM28, SKMel3, WM3248, A375) with IC50 of 4.6-9.3 uM. |
| PC-22521 |
ARN24928
Cdc42 inhibitor
|
ARN24928 is a potent, selective inhibitor of CDC42 GTPases (CDC42, RHOJ, RHOQ), exhibits s antiproliferative activity of melanoma cancer cell lines that have a BRAFV600E mutation (SKM28, SKMel3, WM3248, A375) with IC50 of 3.2-6.9 uM. |
| PC-22520 |
ARN25499
Cdc42 inhibitor
|
ARN25499 is a potent, selective inhibitor of CDC42 GTPases (CDC42, RHOJ, RHOQ), exhibits s antiproliferative activity of melanoma cancer cell lines that have a BRAFV600E mutation (SKM28, SKMel3, WM3248, A375) with IC50 of 8-13.5 uM. |
