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首页-小分子抑制剂&激动剂-Others-Small GTPase-BQU-082
BQU-082

Chemical Structure : BQU-082

CAS No.: 1854910-73-8

BQU-082 (BQU082)

货号: PC-62791Not For Human Use, Lab Use Only.

BQU-082 is a novel potent small GTPase Ral (Ras-like) inhibitor with IC50 of 1.7 uM, displays a dose dependent effect on RalA and RalB activity in H2122 spheroids using the common RalBP1 pull-down assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BQU-082 is a novel potent small GTPase Ral (Ras-like) inhibitor with IC50 of 1.7 uM, displays a dose dependent effect on RalA and RalB activity in H2122 spheroids using the common RalBP1 pull-down assay.

    物理化学性质&存储条件

    分子量 394.438
    分子式 C23H18N6O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-Amino-1,4-dihydro-4-[4-(1H-imidazol-1-yl)phenyl]-1-methyl-3-phenylpyrano[2,3-c]pyrazole-5-carbonitrile

    参考文献

    1. Yan C, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5815-5818.

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