| Cat. No. |
Product Name |
Information |
| PC-25791 |
(6R)-HR3119
RhoGDI2 inhibitor
|
(6R)-HR3119 is a small molecule ligand of Guanine nucleotide dissociation inhibitors (GDIs) protein RhoGDI2 with low-micromolar affinity (Kd= 4 uM), engages with RhoGDI2 in cells and suppresses the migration of aggressive breast cancer cells. |
| PC-25187 |
Rac1 Inhibitor W56
RAC1 inhibitor
|
Rac1 Inhibitor W56 is a peptide inhibitor of Rac1 containing residues 45-60 of Rac1, inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam. |
| PC-24534 |
MLS-573151
Cdc42 inhibitor
|
MLS-573151 (MLS000573151) is a specific small molecule inhibitor of GTPase Cdc42 with EC50 of 2 uM, selective over other Rho family GTPases, including Rac1, Rac 2, RhoA. |
| PC-23015 |
DU101
Arf1 inhibitor
|
DU101 is a potent small molecule inhibitor of small G protein Arf1, binds to the catalytic pocket of the Arf1-GDP-Sec7, inhibit Arf1 activity by binding to Arf1 and Arf-GEF. |