Chemical Structure : ML282
CAS No.: 314042-01-8
货号: PC-62365Not For Human Use, Lab Use Only.
ML282 (CID 1067700) is a competitive small molecule inhibitor of nucleotide binding by Ras-related GTPases, binds the nucleotide binding pocket of Rab7 with Ki value of 13 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥980 | In stock | |
25 mg | ¥1580 | In stock | |
50 mg | ¥2480 | In stock | |
100 mg | Get quote |
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ML282 (CID 1067700) is a competitive small molecule inhibitor of nucleotide binding by Ras-related GTPases, binds the nucleotide binding pocket of Rab7 with Ki value of 13 nM.
ML282 prevents BODIPY-linked GTP and GDP binding with EC50 values of 11.2 and 21 nM, respectively.
ML282 suppresses T cell-dependent and T cell-independent Ab responses.
分子量 | 390.472 | |
分子式 | C18H18N2O4S2 | |
外观性状 | Solid | |
储存条件 |
|
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid |
1. Agola JO, et al. ACS Chem Biol. 2012 Jun 15;7(6):1095-108.
2. Lam T, et al. J Immunol. 2016 Nov 15;197(10):3792-3805.
3. Agola JO, et al. Methods Mol Biol. 2015;1298:331-54.
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