| Cat. No. |
Product Name |
Information |
| PC-36086 |
Avanbulin
Tubulin inhibitor
|
Avanbulin (BAL27862, BAL-27862) is a novel microtubule-destabilizing agent that potently inhibits tubulin assembly at 37°C with IC50 of 1.4 uM in tubulin-binding assays. |
| PC-35925 |
TR-100
Tropomyosin inhibitor
|
TR-100 (TR100) is a specific anti-tropomyosin compound that disrupts the actin cytoskeleton via targeting of Tpm3.1-containing actin filaments. |
| PC-35924 |
ATM-3507
Tropomyosin inhibitor
|
ATM-3507 (ATM3507) is a small molecule inhibitor of Tpm3.1 tropomyosin isoform, disrupts Tpm3.1-containing microfilaments in SK-N-SH cells at 5 uM. |
| PC-35881 |
CCB02
CPAP-tubulin inhibitor
|
CCB02 (CCB 02) is a specific small molecule inhibitor of CPAP-tubulin interaction with IC50 of 0.689 uM in AlphaScreen assay, selectively binds at the CPAP binding site of tubulin. |
| PC-35822 |
6-MOMIPP
Microtubule inhibitor
|
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
| PC-35617 |
MP-HJ-1b
Microtubule inhibitor
|
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
| PC-35599 |
VERU-111 analogue 13f
Tubulin inhibitor
|
VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
| PC-35597 |
VERU-111
Tubulin inhibitor
|
VERU-111 (Sabizabulin, VERU111) is an oral cytoskeleton disruptor that targets and inhibits microtubules to disrupt androgen receptor transport into the nucleus, shows broad antiviral activity by disrupting the intracellular transport of viruses such as SARS CoV-2. |
| PC-43537 |
Eribulin mesylate
Tubulin inhibitor
|
Eribulin mesylate (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-43536 |
Eribulin
Tubulin inhibitor
|
Eribulin (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-35472 |
Valecobulin
Tubulin inhibitor
|
CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo. |
| PC-35334 |
Plocabulin
Tubulin inhibitor
|
Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity, inhibits a panel of 23 tumor cell lines with GI50 of 20 pM-5 nM. |
