| Cat. No. |
Product Name |
Information |
| PC-70178 |
Ombrabulin
Tubulin inhibitor
|
Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.. |
| PC-60252 |
STK899704
Tubulin inhibitor
|
STK899704 is a novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM. |
| PC-42620 |
Lexibulin dihydrochloride
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-42619 |
Lexibulin
Tubulin inhibitor
|
Lexibulin (CYT997) is an orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-45982 |
Cephalomannine
Microtubule stabilizer
|
Cephalomannine is taxol derivative with antitumor, antiproliferative properties, is active in promoting microtubule assembly. |
| PC-42466 |
Ixabepilone
Microtubule stabilizer, TUBB3 inhibitor
|
Ixabepilone (Azaepothilone B, BMS-247550) is a semisynthetic Epothilone B analogue and potent, orally active microtubule stabilizer, also is a TUBB3 inhibitor. |
| PC-45256 |
4-Demethylepipodophyllotoxin
Microtubule inhibitor
|
4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds. |
| PC-45268 |
Fosbretabulin disodium
Microtubule inhibitor
|
Fosbretabulin disodium (CA4DP, Combretastatin A-4) is a derivative of combretastatin that acts as a microtubule destabilising agent, damages the vasculature (blood vessels) of cancer tumours causing central necrosis. |
| PC-45239 |
Vinblastine
Microtubule inhibitor
|
Vinblastine is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer. |
| PC-45151 |
Epothilone B
Microtubule stabilizer
|
Epothilone B (EPO-906, Patupilone) blood-brain barrier-permeable microtubule-stabilizing agent that promotes tubulin polymerization and induces G2-M cell cycle arrest with EC50 of 32 nM in HeLa cells. |
| PC-28770 |
STX140
Microtubule disruptor
|
STX140 is an orally bioavailable anti-angiogenic microtubule disruptor, shows promising anticancer potency both in vitro and in vivo, causes apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells. |
| PC-27335 |
Colchicine
Tubulin inhibitor
|
Colchicine is an orally active alkaloid and potent tubulin inhibitor and a microtubule disrupting agent, inhibits microtubule polymerization with IC50 of 3 nM, also is a competitive antagonist of the α3 glycine receptors (GlyRs). |
