Ombrabulin | Tubulin inhibitor | ProbeChem Biochemicals

Chemical Structure : Ombrabulin

CAS No.: 181816-48-8

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Ombrabulin (AVE8062, AVE 8062A, AC7700, RPR258063)

货号: PC-70178Not For Human Use, Lab Use Only.

Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ..

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10 mg	￥1480	In stock
25 mg	￥2580	In stock
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100 mg		Get quote

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生物&药学活性

Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.
Ombrabulin is a vascular-disrupting agent under clinical investigation combined with cisplatin/docetaxel or carboplatin/paclitaxel in patients with advanced solid tumors.

物理化学性质&存储条件

分子量	402.45
分子式	C21H26N2O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-2-Amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide

参考文献

1. Kim TJ, et al. Cancer Res. 2007 Oct 1;67(19):9337-45.

2. Hori K, et al. Cancer Sci. 2008 Jul;99(7):1485-91.

3. Hori K, et al. Br J Cancer. 2002 May 20;86(10):1604-14.

Ombrabulin (AVE8062, AVE 8062A, AC7700, RPR258063)

生物&药学活性

物理化学性质&存储条件

参考文献

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Ombrabulin (AVE8062, AVE 8062A, AC7700, RPR258063)

生物&药学活性

物理化学性质&存储条件

参考文献

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