ALM201 | Angiogenesis inhibitor | Probechem Biochemicals

Chemical Structure : ALM201

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ALM201 (ALM-201)

货号: PC-38698Not For Human Use, Lab Use Only.

ALM201 is a small 23 amino acid peptide derived from the FK506 binding protein FKBPL, a targeted microtubule binding agent which exhibits potent anti-angiogenic activity in vitro and in vivo.

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生物&药学活性

ALM201 is a small 23 amino acid peptide derived from the FK506 binding protein FKBPL, a targeted microtubule binding agent which exhibits potent anti-angiogenic activity in vitro and in vivo.
ALM201 inhibits endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4.
ALM201 reduced CSCs in ovarian cancer cell lines and primary samples by inducing differentiation.

物理化学性质&存储条件

分子量	2575.819
分子式	C110H179N31O40
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	IRQQPRDPPTETLELEVSPDPAS, Ile-Arg-Gln-Gln-Pro-Arg-Asp-Pro-Pro-Thr-Glu-Thr-Leu-Glu-Leu-Glu-Val-Ser-Pro-Asp-Pro-Ala-Ser

参考文献

1. Martin O'Rourke, et al. Cancer Res (2011) 71 (8_Supplement): 3288.

ALM201 (ALM-201)

生物&药学活性

物理化学性质&存储条件

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ALM201 (ALM-201)

生物&药学活性

物理化学性质&存储条件

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