| Cat. No. |
Product Name |
Information |
| PC-42953 |
RGDS peptide
Integrin inhibitor
|
RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin. |
| PC-62157 |
LLP2A
α4β1 integrin ligand
|
LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM. |
| PC-62071 |
TC-I 15
α2β1 integrin inhibitor
|
TC-I 15 is a highly potent, selective, allosteric small-molecule inhibitor of integrin α2β1 with IC50 of 12 nM. |
| PC-62001 |
MK-0429
αvβ3 integrin inhibitor
|
MK-0429 (L-000845704) is a potent, selective, orally-active nonpeptide αvβ3 integrin inhibitor with IC50 of 0.08 nM in SPAV3 assay. |
| PC-61417 |
JK-273
α4 integrin inhibitor
|
JK-273 is a small molecule inhibitor of α4 integrin-dependent cell migration (IC50=0.5 uM, on the motility of Jurkat T cells) that functions by interacting with γ-parvin. |
| PC-61300 |
BIO5192
Integrin α4β1 inhibitor
|
BIO5192 (BIO-5192) is a potent, highly selective inhibitor of integrin α4β1 (VLA-4) with Kd of <10 pM, IC50 of 1.8 nM. |
| PC-61261 |
TBC3486
α4β1 integrin inhibitor
|
TBC3486 is a potent, selective, non-peptidic integrin α4β1 (VLA-4) antagonist with IC50 of 9 nM, displays 200-fold selectivity over α4β7 (IC50=2.1 uM). |
| PC-61134 |
ML165
αIIbβ3 integrin inhibitor
|
ML165 (RUC-2) is a high-affinity, selective platelet integrin αIIbβ3 receptor antagonist with IC50 of 96 nM. |
| PC-61133 |
RUC-4
αIIbβ3 integrin inhibitor
|
Zalunfiban (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors. |
| PC-60253 |
Leukadherin-1
CD11b agonist
|
Leukadherin-1 (LA1) is a small molecule allosteric agonist of integrin CD11b/CD18 (CR3), increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50=4 uM). |
| PC-70068 |
Cyclo(RGDyK)
αvβ3 integrin inhibitor
|
Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM. |
| PC-70014 |
BIO-7662
Integrin α4β1 inhibitor
|
BIO-7662 (BIO7662) is a potent, highly selective α4β1 integrin antagonist with Kd of <10 pM. |
