LLP2A | α4β1 integrin ligand | Probechem Biochemicals

Chemical Structure : LLP2A

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LLP2A (α4β1 integrin inhibitor)

货号: PC-62157Not For Human Use, Lab Use Only.

LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.

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100 mg		Get quote

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生物&药学活性

LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.
LLP2A shows no binding affinity for α2β1, α6β1, αLβ2 and αMβ2 integrins.
LLP2A can be used to image α4β1-expressing lymphomas with high sensitivity and specificity when conjugated to a near infrared fluorescent dye in a mouse xenograft model.

物理化学性质&存储条件

分子量	810.953
分子式	C43H54N8O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-6-((1-carbamoylcyclohexyl)amino)-6-oxo-5-((S)-6-((E)-3-(pyridin-3-yl)acrylamido)-2-(2-(4-(3-(o-tolyl)ureido)phenyl)acetamido)hexanamido)hexanoic acid

参考文献

1. Peng L, et al. Nat Chem Biol. 2006 Jul;2(7):381-9.

2. Beaino W, et al. J Nucl Med. 2014 Nov;55(11):1856-63.

3. Soodgupta D, et al. J Nucl Med. 2016 Apr;57(4):640-5.

LLP2A (α4β1 integrin inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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LLP2A (α4β1 integrin inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

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