Integrin (inhibitors, antagonists, modulators)-ProbeChem.com

Request The Product List ofIntegrin Integrin

Cat. No.	Product Name	Information
PC-27620	BTT-3033 α2β1 integrin inhibitor	BTT-3033 is a specific small molecule α2β1 integrin (GPIa/IIa, VLA-2) inhibitor, inhibits CHO-α2wt cells adhesion to rat tail collagen I with EC50 of 130 nM, binds to the α2I domain.
PC-27179	C19-9N αv/α5β1 integrin antagonist	C19-9N is a potent, orally bioavailable pan-αv/α5β1 integrin antagonist, exhibits high affinity for αvβ3 (Kd=0.55 μM), αvβ5 (Kd=0.61 μM), α5β1 (Kd=0.88 μM), αvβ6 (Kd=0.41 μM) and αvβ8 (Kd=0.86 μM), blocks extracellular matrix (ECM)-integrin interaction.
PC-25047	GS-1069518 α4β7 integrin inhibitor	GS-1069518 is a potent and selective α4β7 integrin inhibitor.
PC-24715	Zalunfiban dihydrochloride αIIbβ3 integrin antagonist	Zalunfiban dihydrochloride (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
PC-24102	RO0270608 Integrin α4β1/α4β7 inhibitor	RO0270608 is the active metabolite of Valategrast (R411), which is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
PC-23193	Carotegrast α4 integrin inhibitor	Carotegrast (HCA2969) is a novel potent, selective, oraaly available alpha 4 integrin antagonist.

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