| Cat. No. |
Product Name |
Information |
| PC-42058 |
TA-01
CK1δ/ε inhibitor, p38α inhibitor
|
TA-01 is a potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively. |
| PC-23588 |
Fam20C inhibitor 5k
Fam20C inhibitor
|
Fam20C inhibitor 5k is a potent small-molecule Fam20C inhibitor with IC50 of 2.1 uM, showspotent anti-proliferative activity against MDA-MB-231 and BT-549 cells with IC50 values of 11.8 uM and 9.7 uM, respectively. |
| PC-23106 |
CKIP-1 ligand C77
CKIP-1 ligand
|
CKIP-1 ligand C77 is a small molecule ligand of casein kinase 2 interacting protein-1 (CKIP-1) with SPR KD of 27.12 nM. |
| PC-22790 |
CX-5011
CK2 inhibitor
|
CX-5011 is a potent, selective inhibitor of protein kinase CK2 with IC50 of <10 nM, induces cell death by apoptosis and acts synergistically with imatinib or the MEK-inhibitor U0126 in imatinib-resistant CML cells. |
| PC-22407 |
SGC-CK2-2
CK2 inhibitor
|
SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945). |
| PC-22273 |
ARC-3140
CK2 inhibitor
|
ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22272 |
ARC-1502
CK2 inhibitor
|
ARC-1502 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 0.56 nM, addressing the ATP site and the substrate-binding site of CK2. interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22047 |
CK2 inhibitor 7h
CK2 inhibitor
|
CK2 inhibitor 7h is a potent, selective Casein Kinase 2 (CK2) inhibitor with IC50 of <3 nM and SPR KD of 6.33 pM, pAKTS129 IC50 of 4 nM. |
| PC-21783 |
AB668
CK2 inhibitor
|
AB668 is a selective, bivalent Casein Kinase 2 (CK2) inhibitor targeting the ATP site and the αD pocket, AB668 inhibits the CK2 holoenzyme with Ki value of 41 nM (IC50=65 nM). |
| PC-21547 |
CKR-49-17
CK1γ2 activator
|
CKR-49-17 is a potent, allosteric small molecule activator of CK1γ2 with Kd value of 180 nM in MST assays. |
| PC-20908 |
SGC-CK2-1 analog 2h
CK2α inhibitor
|
SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively. |
| PC-20823 |
SR-4133
CK1ε inhibitor
|
SR-4133 (SR4133) is a potent and highly selective CK1ε isoform inhibitor with IC50 of 58 nM, no significant acitivity agianst CK1δ (IC50>10,000 nM). |
