| Cat. No. |
Product Name |
Information |
| PC-26318 |
VRK1/CK1-IN-1
VRK1/CK1 inhibitor
|
VRK1/CK1-IN-1 is a potent, dual inhibitor of Vaccinia-related kinase 1 (VRK1) and the δ and ε isoforms of casein kinase 1 (CK1) with Ki of 37.9 nM for VRK1, and IC50 of 17 nM and 15 nM for CK1δ and CK1ε, mimics the cellular outcomes of VRK1 depletion. |
| PC-26111 |
GW869516X
CK2 inhibitor
|
GW869516X is a highly potent casein kinase 2 (CK2) inhibitor with IC50 of 85 nM and 34 nM for CSNK2A1 (CK2α) and CSNK2A2 (CK2α') in recombinant kinase assays, and IC50 of 446 and 319 nM in NanoBRET assays. |
| PC-26004 |
BMS-159
CK2 inhibitor
|
BMS-159 is the orally bioavailabile phosphate prodrug of BMS-135, which is a potent, ATP-competitive inhibitor of Casein kinase 2 (CK2), exhibits subnanomolar potency against both CK2α and CK2α′ isoforms with IC50 of 0.8 nM and 0.3 nM, respectively. |
| PC-26003 |
BMS-135
CK2 inhibitor
|
BMS-135 is a potent, ATP-competitive inhibitor of Casein kinase 2 (CK2), exhibits subnanomolar potency against both CK2α and CK2α′ isoforms with IC50 of 0.8 nM and 0.3 nM, respectively. |
| PC-25908 |
IGS-2.7
CK1δ inhibitor
|
IGS-2.7 is a potent, selective and brain permeable CK1delta (CK-1δ, CK1δ) inhibitor with IC50 of 23 nM, >35-fold selective over CK1ε (IC50=840 nM). |
| PC-25590 |
CK1γ inhibitor 1h
CK1γ inhibitor
|
CK1γ inhibitor 1h is a potent, selective inhibitor of casein kinase 1γ (CK1γ) with IC50 of 18 nM, has >100-fold selective over CK1α, CK1δ and GSK3β, inhibits phosphorylation of LRP6 in HEK293 cell with IC50 of 0.7 uM. |
| PC-25589 |
FP1-24
CK1γ inhibitor
|
FP1-24 (CK1γ Inhibitor 13) is a potent and selective CK1γ inhibitor with IC50 of 5 nM, with 8- and 50-fold selective over CK1δ and CK1α respectively, and shows activity against GSK3β. |
| PC-25588 |
SGC-CK1γ-1
CK1γ inhibitor
|
SGC-CK1γ-1 is the first chemical probe inhibitor of casein kinase 1γ (CK1γ) subfamily (CK1γ1, CK1γ2, and CK1γ3) with IC50 of 180,180 and 230 nM in NanoBRET assays respectively, inhibits both WNT signaling and human cytomegalovirus replication. |
| PC-25109 |
IOR-160
CK2/HDAC inhibitor
|
IOR-160 is a potent dual inhibitor of casein kinase 2 (CK2) and HDAC with IC50 of 1.7 nM for CK2 and 3.3/24.0/3.9/13.0 nM for HDAC1/2/3/6 respectively. |
| PC-24728 |
PF-4800567
CK1ε inhibitor
|
PF-4800567 is a potent, selective inhibitor of casein kinase 1 epsilon (CK1epsilon, CK1ε) with IC50 of 32 nM, >20-fold selectivity over CK1δ. |
| PC-24636 |
Chrysoeriol
CK2 inhibitor
|
Chrysoeriol is a natural product for CK2 (Casein kinase 2) inhibitor with IC50 of 0.5 uM, inhibits JAK2/STAT3, IκB/p65, and NF-κB pathways, shows strong anti-inflammatory activities. |
| PC-24635 |
FNH79
CK2 inhibitor
|
FNH79 is a highly selective and potent CK2 (Casein kinase 2) inhibitor with IC50 of 4 nM. |
