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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase

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Cat. No. Product Name Information
PC-21547

CKR-49-17

CK1γ2 activator

CKR-49-17 is a potent, allosteric small molecule activator of CK1γ2 with Kd value of 180 nM in MST assays.
PC-20908

SGC-CK2-1 analog 2h

CK2α inhibitor

SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively.
PC-20823

SR-4133

CK1ε inhibitor

SR-4133 (SR4133) is a potent and highly selective CK1ε isoform inhibitor with IC50 of 58 nM, no significant acitivity agianst CK1δ (IC50>10,000 nM).
PC-35615

BMS-211

BMS-211 is a prodrug of the parent pan-CK2 inhibitor BMS-699..
PC-60384

Pyrvinium Iodide

An anthelmintic effective for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity.

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