| Cat. No. |
Product Name |
Information |
| PC-25590 |
CK1γ inhibitor 1h
CK1γ inhibitor
|
CK1γ inhibitor 1h is a potent, selective inhibitor of casein kinase 1γ (CK1γ) with IC50 of 18 nM, has >100-fold selective over CK1α, CK1δ and GSK3β, inhibits phosphorylation of LRP6 in HEK293 cell with IC50 of 0.7 uM. |
| PC-25589 |
FP1-24
CK1γ inhibitor
|
FP1-24 (CK1γ Inhibitor 13) is a potent and selective CK1γ inhibitor with IC50 of 5 nM, with 8- and 50-fold selective over CK1δ and CK1α respectively, and shows activity against GSK3β. |
| PC-25588 |
SGC-CK1γ-1
CK1γ inhibitor
|
SGC-CK1γ-1 is the first chemical probe inhibitor of casein kinase 1γ (CK1γ) subfamily (CK1γ1, CK1γ2, and CK1γ3) with IC50 of 180,180 and 230 nM in NanoBRET assays respectively, inhibits both WNT signaling and human cytomegalovirus replication. |
| PC-25109 |
IOR-160
CK2/HDAC inhibitor
|
IOR-160 is a potent dual inhibitor of casein kinase 2 (CK2) and HDAC with IC50 of 1.7 nM for CK2 and 3.3/24.0/3.9/13.0 nM for HDAC1/2/3/6 respectively. |
| PC-24636 |
Chrysoeriol
CK2 inhibitor
|
Chrysoeriol is a natural product for CK2 (Casein kinase 2) inhibitor with IC50 of 0.5 uM, inhibits JAK2/STAT3, IκB/p65, and NF-κB pathways, shows strong anti-inflammatory activities. |
| PC-24635 |
FNH79
CK2 inhibitor
|
FNH79 is a highly selective and potent CK2 (Casein kinase 2) inhibitor with IC50 of 4 nM. |
| PC-24634 |
CK2A2 inhibitor 65
CK2A2 inhibitor
|
CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively. |
| PC-23901 |
PF670462 dihydrochloride
CK1ε/CK1δ inhibitor
|
PF-670462 dihydrochloride (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively. |
| PC-23900 |
MU1742
CK1 inhibitor
|
MU1742 is a potent, selective inhibitor of Casein kinases 1 (CK1) with IC50 of 7/6/28 nM for CK1α/CK1δ/CK1ε respectively, does not inhibit p38α. |
| PC-23588 |
Fam20C inhibitor 5k
Fam20C inhibitor
|
Fam20C inhibitor 5k is a potent small-molecule Fam20C inhibitor with IC50 of 2.1 uM, showspotent anti-proliferative activity against MDA-MB-231 and BT-549 cells with IC50 values of 11.8 uM and 9.7 uM, respectively. |
| PC-23106 |
CKIP-1 ligand C77
CKIP-1 ligand
|
CKIP-1 ligand C77 is a small molecule ligand of casein kinase 2 interacting protein-1 (CKIP-1) with SPR KD of 27.12 nM. |
| PC-22790 |
CX-5011
CK2 inhibitor
|
CX-5011 is a potent, selective inhibitor of protein kinase CK2 with IC50 of <10 nM, induces cell death by apoptosis and acts synergistically with imatinib or the MEK-inhibitor U0126 in imatinib-resistant CML cells. |
