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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase-DFMNTU
DFMNTU

Chemical Structure : DFMNTU

CAS No.: 313391-88-7

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DFMNTU

货号: PC-28443Not For Human Use, Lab Use Only.

DFMNTU is a small molecule casein kinase 2 (CK2) inhibitor with IC50 of 22 uM for CK2α, potently inhibits Yellow fever virus (YFV)-induced cytopathic effects with EC50 of 4.3 ug/mL(neutral red uptake) and 2.4 ug/mL (visual CPE assessment).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DFMNTU is a small molecule casein kinase 2 (CK2) inhibitor with IC50 of 22 uM for CK2α, potently inhibits Yellow fever virus (YFV)-induced cytopathic effects with EC50 of 4.3 ug/mL(neutral red uptake) and 2.4 ug/mL (visual CPE assessment).

物理化学性质&存储条件

分子量 425.45
分子式 C22H17F2N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-[4-(2- difluoromethoxyphenyl)- 5- methylthiazol- 2- yl]- 3-(naphthalen- 1- yl)urea

参考文献

1. Demchenko A, et al. Eur J Pharm Sci. 2026 Oct 3:107679.

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