| Cat. No. |
Product Name |
Information |
| PC-60432 |
MW-150 hydrochloride
p38α inhibitor
|
MW-150 hydrochloride is a potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM. |
| PC-45059 |
Acumapimod
p38 MAPK inhibitor
|
An orally active, potent p38 MAPK inhibitor that potently inhibits ex vivo LPS‐induced TNFα secretion with an IC50 of 44 ng/mL (115 nM). |
| PC-42491 |
SB203580
p38 MAPK inhibitor
|
SB203580 (Adezmapimod, RWJ 64809) is a specific p38 MAPK inhibitor with IC50 of 0.6 uM. |
| PC-42564 |
Losmapimod
p38 MAPK inhibitor
|
Losmapimod (GSK-AHAB, GW856553X, SB856553) is a selective, potent, orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. |
| PC-45452 |
SB-242235
p38 MAPK inhibitor
|
SB-242235 is a selective p38 MAPK inhibitor, inhibits IL-1 beta induction of p38 MAPK in primary human chondrocytes with IC50 of 1 uM. |
| PC-42563 |
VX-702
p38 MAPK inhibitor
|
VX-702 is a potent, selective, second generation p38 MAPK inhibitor with IC50 of 4-20 nM for p38α. |
| PC-42565 |
Pamapimod
p38α MAPK inhibitor
|
Pamapimod (Ro4402257; R1503) is a potent, selective, orally bioavailable p38α MAPK inhibitor with Kd of 0.2 nM. |
| PC-42803 |
SB 239063
p38 MAPK inhibitor
|
SB 239063 is a potent, selective, orally available p38 MAPK inhibitor with IC50 of 44 nM for both p38α and p38β. |
| PC-42599 |
TAK-715
p38α inhibitor
|
TAK-715 is a potent, selective, orally active p38α MAPK inhibitor with IC50 of 7.1 nM. |
| PC-42566 |
SCIO-469
p38α MAPK inhibitor
|
Talmapimod (SCIO469) is a potent, selective p38α MAPK inhibitor with IC50 of 9 nM. |
| PC-42662 |
PD 169316
p38 MAPK inhibitor
|
PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM. |
| PC-42059 |
TA-02
p38 MAPK inhibitor
|
TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM. |
