| Cat. No. |
Product Name |
Information |
| PC-63395 |
JNJ-49095397
p38 MAPK inhibitor
|
JNJ-49095397 (RV-568) is a specific narrow-spectrum kinase inhibitor that inhibits a selected set of kinases involved in COPD inflammation with IC50 of 5, 40 and 52 nM for p38α, p38γ and HCK, respectively. |
| PC-63284 |
AZD-7624
p38α MAPK inhibitor
|
AZD-7624 (AZD7624) is a potent, selective, inhaled p38α MAPK inhibitor with pIC50 of 10.0, displays 15-fold selectivity for p38α over p38β MAPK and >10,000-fold selectivity over p38γ and p38δ MAPK. |
| PC-43421 |
LY2228820 dimesylate
p38 MAPK inhibitor
|
LY2228820 dimesylate (Ralimetinib) is a potent, selective, orally available inhibitor p38 MAPK with IC50 of 5.3 and 3.2 nM for p38α and p38β, respectively. |
| PC-43250 |
p38 MAPK-IN-4
p38 MAPK inhibitor
|
p38 MAPK-IN-4 is a potent and selective inhibitor of p38 MAPK with IC50 of 68 nM for p38α, inhibits LPS-induced TNFα release in THP-1 cells with IC50 of 187 nM. |
| PC-43080 |
SKF-86002
p38 MAPK inhibitor
|
SKF-86002 is a potent inhibitor of p38 MAPK with IC50 of 0.5-1 uM, inhibits LPS-induced IL-1 and TNF-α production in human monocyte with IC50 of 1 uM. |
| PC-42805 |
SD0006
p38α inhibitor
|
SD0006 (SD-0006, SD-06) is a potent, selective, ATP-competitive and orally bioavailable p38α inhibitor with Ki of 61 nM. |
| PC-63103 |
PF-03715455
p38α inhibitor
|
PF-03715455 is a highly potent and selective inhibitor for p38α MAPK with IC50 of 1.6 nM. |
| PC-63000 |
AW-814141
p38 MAPK inhibitor
|
AW-814141 (AW814141) is a potent, selective and orally active inhibitor of p38 MAP kinase with IC50 of 100 nM/158 nM for p38α/p38β. |
| PC-62783 |
MW181 dihydrochloride
p38α MAPK inhibitor
|
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
| PC-62782 |
MW181 hydrochloride
p38α inhibitor
|
MW181 hydrochloride is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
| PC-62781 |
MW181
p38α inhibitor
|
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
| PC-62614 |
NJK14047
p38 MAPK inhibitor
|
NJK14047 is a novel potent, selective p38 MAPK inhibitor with IC50 of 27 nM against p38α, suppresses RSV and influenza A virus replication by inhibiting virus-induced p38 MAPK activation. |
