| Cat. No. |
Product Name |
Information |
| PC-22421 |
TRPV1 antagonist CX-3
TRPV1 antagonist
|
TRPV1 antagonist CX-3 is a first-in-class highly selective TRPV1 antagonist with IC50 of 26.2 nM, inhibits TRPV1 current with IC50 value of 9.71 uM in whole-cell patch-clamp assay. |
| PC-22256 |
TRPM5 agonist 64
TRPM5 agonist
|
TRPM5 agonist 64 is a potent, selective TRPM5 agonist with pEC50 of 7.8 and .1 for mTRPM5 and hTRPM5, respectively. |
| PC-22170 |
TRPV2 antagonist SET2
TRPV2 antagonist
|
SET2 is a potent, subtype-selective inhibitor of transient receptor potential vanilloid type 2 (TRPV2) with IC50 of 0.46 uM. |
| PC-22127 |
SOR-C13 TFA
TRPV6 inhibitor
|
SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM. |
| PC-22083 |
PCC0208057
TRPC6 inhibitor
|
PCC0208057 is a potent, selective TRPC6 channel inhibitor, inhibits TRPC6-mediated Ca2+ concentration increase with IC50 of 2.44 uM, binds directly to TRPC6. |
| PC-21344 |
M085
TRPC3/6/7 activator
|
M085 (TRPC3/6/7 activator 4o) is a potent and selective TRPC3/6/7 activator with EC50 of 4.66 uM, also activates hTRPC6 with EC50 of 3.8 uM. |
| PC-21342 |
Hyperforin Dicyclohexylammonium Salt
TRPC6 activator
|
Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms. |
| PC-21131 |
AAL-149
TRPM7 inhibitor
|
AAL-149 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 1.081 uM, shows potent anti-inflammatory effects in vivo. |
| PC-21060 |
MK6-83
TRPML1 agonist
|
MK6-83 is a specific transient receptor potential mucolipin -1 (TRPML1/MCOLN1) agonist, activates the entire endosomal TRPML1 current in DMD myocytes with EC50 of 285 nM. |
| PC-49443 |
AMG21629
TRPV1 antagonist
|
AMG21629 is a potent and selective TRPV1 antagonist, inhibits Ca2+ uptake by CHO cells expressing TRPV1 receptors with IC50 of 0.6 nM and 0.8 nM for capsaicin and acid-induced Ca2+ uptake, respectively. |
| PC-73173 |
ML-SI3
TRPML inhibitor
|
ML-SI3 is a synthetic inhibitor of TRPML calcium channel blocker. |
| PC-63429 |
JNJ-38893777 sulfate
|
JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.. |
