欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-AC1903
AC1903

Chemical Structure : AC1903

CAS No.: 831234-13-0

加入收藏

AC1903 (AC-1903)

货号: PC-60025Not For Human Use, Lab Use Only.

AC1903 is a potent, specific TRPC5 channel inhibitor with IC50 of 14.7 uM.

规格 价格 库存 数量
25 mg ￥2180 In stock
50 mg ￥3780 In stock
100 mg ￥5980 In stock
500 mg ￥9580 In stock
1 g Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AC1903 is a potent, specific TRPC5 channel inhibitor with IC50 of 14.7 uM.
AC1903 blocks riluzole-activated TRPC5 whole-cell current, but fails to block carbachol (CCh)-induced TRPC4 and OAG-induced TRPC6 currents, even at high micromolar concentrations.
AC1903 pecifically blocks TRPC5 channel activity in glomeruli of proteinuric rats, suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of FSGS.

物理化学性质&存储条件

分子量 303.365
分子式 C19H17N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

100 mM in DMSO (30.3 mg/mL)
Chemical Name/SMILES

1-benzyl-N-(furan-2-ylmethyl)-1H-benzo[d]imidazol-2-amine

参考文献

1. Zhou Y, et al. Science. 2017 Dec 8;358(6368):1332-1336.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: