2-APB |CAS:524-95-8 Probechem Biochemicals

Chemical Structure : 2-APB

CAS No.: 524-95-8

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2-APB (2ABP;2-Aminoethoxydiphenylborane)

货号: PC-60019Not For Human Use, Lab Use Only.

2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker.

规格	价格	库存
50 mg	￥780	In stock
100 mg	￥1280	In stock
250 mg	￥1980	In stock
1 g		Get quote

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生物&药学活性

2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker.
2-APB stimulates store-operated calcium (SOC) release at 10 uM,.
2-APB ncreases STIM-Orai channel conductance and limits ion selectivity.

物理化学性质&存储条件

分子量	225.094
分子式	C14H16BNO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	100 mM in DMSO
Chemical Name/SMILES	2-Aminoethoxydiphenylborane

参考文献

1. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5.

2. Maruyama T, et al. J Biochem. 1997 Sep;122(3):498-505.

3. Bai D, et al. J Pharmacol Exp Ther. 2006 Dec;319(3):1452-8.

4. Togashi K, et al. Br J Pharmacol. 2008 Mar;153(6):1324-30.

2-APB (2ABP;2-Aminoethoxydiphenylborane)

生物&药学活性

物理化学性质&存储条件

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2-APB (2ABP;2-Aminoethoxydiphenylborane)

生物&药学活性

物理化学性质&存储条件

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