| Cat. No. |
Product Name |
Information |
| PC-35102 |
TL02-59
Fgr kinase inhibitor
|
TL02-59 is a potent, selective, orally available inhibitor of Src-family kinase Fgr IC50 of 0.03 nM, also inhibits Lyn and Hck with IC50 of 0.1 and 160 nM, respectively. |
| PC-63531 |
KX2-361
Src/tubulin inhibitor
|
KX2-361 (KX 02) is a potent, orally active dual Src signaling/tubulin polymerization inhibitor, KX2-361 is a non-ATP competitive Src inhibitor, demonstrates broad anti-tumor activity both in vitro and in vivo. |
| PC-63476 |
UM-164
c-Src/p38 inhibitor
|
UM-164 is a movel potent, dual c-Src/p38 with Kd of 2.7 nM (c-Src), potently inhibits both p38α and p38β. |
| PC-42962 |
WH-4-023
Lck/Src inhibitor
|
WH-4-023 (KIN-112) is a potent and selective dual Lck/Src inhibitor with IC50 of 0.6 nM/1 nM for Lck and Src kinase respectively, displays little to no inhibition on p38α, Btk, KDR (IC50>100 nM). |
| PC-42886 |
Lck Inhibitor 25
Lck inhibitor
|
Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38. |
| PC-62865 |
KB SRC 4
Src inhibitor
|
KB SRC 4 (c-Src-IN-4) is a potent, highly selective c-Src kinase inhibitor with Ki of 44 nM, does not inhibit c-Abl up to 125 uM, and binds to c-Src-TM (Q275G, C277Q, F278Y) with similar potency to that of wild-type c-Src. |
| PC-62498 |
AZD0424
Src/Abl inhibitor
|
AZD 0424 is an orally bioavailable small molecule tyrosine kinase inhibitor of Abl and Src kinase with potential antineoplastic activity.. |
| PC-61227 |
NMT1 inhibitor B13
NMT1 inhibitor
|
NMT1 inhibitor B13 (LCL4, D-NMAPPD) is a myristoylCoA analog that acts as a small molecule inhibitor of N-myristoyltransferase 1 (NMT1) with IC50 of 77.6 uM, blocks Src myristoylation and Src localization to the cytoplasmic membrane. |
| PC-61226 |
LCL204
NMT1 inhibitor
|
LCL204 is a small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4. |
| PC-70245 |
Src I338G-IN-3g
I338G v-Src inhibitor
|
A potent, selective, cell-permeable I338G v-Src inhibitor with IC50 of 430 nM, shows no inhibition of wild-type v-Src at 300 uM. |
| PC-61141 |
eCF506
Src inhibitor
|
eCF506 (NXP900) is a highly potent, selective, orally available Src family kinase inhibitor with IC50 of <0.5 nM, <0.5 nM and for Src, Yes and Fyn kinases respectively, >950-fold selectivity for Src over ABL. |
| PC-60888 |
PD166285
Src/Wee1/Myt1 inhibitor
|
PD166285 (PD 0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM, also inhibits the checkpoint kinases Wee1 and Myt1. |
