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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Src

Request The Product List ofSrc Src

Cat. No. Product Name Information
PC-42962

WH-4-023

Lck/Src inhibitor

WH-4-023 (KIN-112) is a potent and selective dual Lck/Src inhibitor with IC50 of 0.6 nM/1 nM for Lck and Src kinase respectively, displays little to no inhibition on p38α, Btk, KDR (IC50>100 nM).
PC-42886

Lck Inhibitor 25

Lck inhibitor

Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38.
PC-62865

KB SRC 4

Src inhibitor

KB SRC 4 (c-Src-IN-4) is a potent, highly selective c-Src kinase inhibitor with Ki of 44 nM, does not inhibit c-Abl up to 125 uM, and binds to c-Src-TM (Q275G, C277Q, F278Y) with similar potency to that of wild-type c-Src.
PC-62498

AZD0424

Src inhibitor

AZD 0424 is an orally bioavailable small molecule tyrosine kinase inhibitor of Abl and Src kinase with potential antineoplastic activity..
PC-61227

NMT1 inhibitor B13

NMT1 inhibitor

NMT1 inhibitor B13 (LCL4, D-NMAPPD) is a myristoylCoA analog that acts as a small molecule inhibitor of N-myristoyltransferase 1 (NMT1) with IC50 of 77.6 uM, blocks Src myristoylation and Src localization to the cytoplasmic membrane.
PC-61226

LCL204

NMT1 inhibitor

LCL204 is a small molecule that inhibits N-myristoyltransferase (NMT1) with IC50 of 8.7 uM, 10-fold enhanced inhibitory potency than LCL4.
PC-70245

Src I338G-IN-3g

I338G v-Src inhibitor

A potent, selective, cell-permeable I338G v-Src inhibitor with IC50 of 430 nM, shows no inhibition of wild-type v-Src at 300 uM.
PC-61141

eCF506

Src inhibitor

eCF506 (NXP900) is a highly potent, selective, orally available Src family kinase inhibitor with IC50 of <0.5 nM, <0.5 nM and for Src, Yes and Fyn kinases respectively, >950-fold selectivity for Src over ABL.
PC-60888

PD166285

Src/Wee1/Myt1 inhibitor

PD166285 (PD 0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM, also inhibits the checkpoint kinases Wee1 and Myt1.
PC-60584

JP-153

Src inhibitor

JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs.
PC-70182

TX-1123

Src inhibitor

TX-1123 is a tyrphostin AG17 analog that exihibits potent Src kinase inhibitory activity with IC50 of 2.2 uM.
PC-70102

Damnacanthal

p56lck inhibitor

Damnacanthal is a highly potent, selective inhibitor of p56 lck tyrosine kinase with IC50 of 17 nM for inhibition of p56lck autophosphorylation.

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