| Cat. No. |
Product Name |
Information |
| PC-45439 |
KX1-004
Src inhibitor
|
KX1-004 is a non-ATP competitive Src-PTK inhibitor with IC50 of 40 uM. |
| PC-42539 |
KX2-391 mesylate
Src/pretubulin inhibitor
|
Tirbanibulin mesylate (KX2-391 mesylate) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-42538 |
KX2-391 dihydrochloride
Src inhibitor
|
Tirbanibulin (KX2-391 dihydrochloride) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-42537 |
KX2-391
Src inhibitor
|
KX2-391(Tirbanibulin, KX 01, KX 2-391) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-25816 |
DCDBS84 hydrobromide
Integrin β3-Src SH3 inhibitor
|
DCDBS84 hydrobromide is a small molecule specifically targeting c‐Src SH3 RT‐loop with SPR Kd of 0.83 uM, disrupts the interaction of integrin β3 with Src SH3, selectively blocks αIIbβ3 outside‐in signaling and shows potent antithrombotic effect. |
| PC-25815 |
DCDBS84
Integrin β3-Src SH3 inhibitor
|
DCDBS84 is a small molecule specifically targeting c‐Src SH3 RT‐loop with SPR Kd of 0.83 uM, disrupts the interaction of integrin β3 with Src SH3, selectively blocks αIIbβ3 outside‐in signaling and shows potent antithrombotic effect. |
| PC-25344 |
Reynoutrin
Fyn inhibitor
|
Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from Psidium cattleianum, with antioxidant and radical-scavenging activity, a potent inhibitor of Fyn, inhibits both the expression and phosphorylation of Fyn. |
| PC-24574 |
Src inhibitor PP1
Src inhibitor
|
PP1 is a potent, selective Src family tyrosine kinases inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively. |
| PC-24573 |
Src inhibitor PP2
Src inhibitor
|
PP2 is a potent, reversible and ATP-competitive Src family kinases inhibitor with IC50 of 4 and 5 nM for Lck and Fyn, respectively, also inhibits RIPK3 with IC50 of 29 nM. |
| PC-24043 |
Bosutinib hydrate
Src/Abl inhibitor
|
Bosutinib hydrate (SKI-606) is a potent, dual Src/Abl inhibitor with IC50 of 1.2 nM (Src enzyme), inhibits Src autophosphorylation with an IC50 of 0.25 uM in HT29 cells, inhibits bacterially expressed Abl kinase activity with IC50 of 1 nM. |
| PC-24042 |
Bosutinib
Src/Abl inhibitor
|
Bosutinib (SKI-606) is a potent, dual Src/Abl inhibitor with IC50 of 1.2 nM (Src enzyme), inhibits Src autophosphorylation with an IC50 of 0.25 uM in HT29 cells, inhibits bacterially expressed Abl kinase activity with IC50 of 1 nM. |
| PC-22492 |
(R)-LW-Srci-8
c-Src inhibitor
|
(R)-LW-Srci-8 is a potent, selective, covalent inhibitor of autophosphorylation site in c-Src kinase with IC50 of 35.83 nM. |