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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Src-AMG-47a
AMG-47a

Chemical Structure : AMG-47a

CAS No.: 882663-88-9

AMG-47a (AMG47a)

货号: PC-45449Not For Human Use, Lab Use Only.

AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AMG-47a is a potent Lck kinase inhibitor with IC50 of 0.2 nM, selectively reduces the levels of EGFP-KRASG12V protein but do not affect EGFP protein in cells.

物理化学性质&存储条件

分子量 535.5601
分子式 C29H28F3N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

Benzamide, 4-methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]-

参考文献

1. Carver J, et al. PLoS One. 2014 Aug 5;9(8):e103836.

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