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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Src-KX1-004
KX1-004

Chemical Structure : KX1-004

CAS No.: 518058-84-9

KX1-004 (KX1 004)

货号: PC-45439Not For Human Use, Lab Use Only.

KX1-004 is a non-ATP competitive Src-PTK inhibitor with IC50 of 40 uM.

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5 mg ¥1180 In stock
10 mg ¥1780 In stock
25 mg ¥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KX1-004 is a non-ATP competitive Src-PTK inhibitor with IC50 of 40 uM.
KX1-004 has potential protective for noise-induced hearing loss (NIHL).
KX1-004 significantly reduces cisplatin-induced hearing loss in nude rats with implanted HT-29 tumors.

物理化学性质&存储条件

分子量 284.285
分子式 C16H13FN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 42 mg/mL

Chemical Name/SMILES

1H-Indole-2-carboxamide, 5-fluoro-N-[(3-hydroxyphenyl)methyl]-

参考文献

1. Harris KC, et al. Hear Res. 2005 Oct;208(1-2):14-25.

2. Bielefeld EC, et al. Noise Health. 2005 Oct-Dec;7(29):24-30.

3. Bielefeld EC, et al. Anticancer Drugs. 2013 Jan;24(1):43-51.

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