Lck Inhibitor 25 |CAS:847950-09-8 Probechem Biochemicals

Chemical Structure : Lck Inhibitor 25

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Lck Inhibitor 25

货号: PC-42886Not For Human Use, Lab Use Only.

Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38.

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生物&药学活性

Lck Inhibitor 25 is a potent, selective Lck kinase inhibitor with IC50 of 7 nM, weakly inhibits Src and Lyn with IC50 of 42 and 21 nM, does not inhibits KDE and p38.
Lck Inhibitor 25 inhibits T cell proliferation in vitro and inhibits arthritis in in vivo models.

物理化学性质&存储条件

分子量	530.6229
分子式	C31H30N8O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one, 6-(2,6-dimethylphenyl)-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-

参考文献

1. Martin MW, et al. J Med Chem. 2008 Mar 27;51(6):1637-48.

Lck Inhibitor 25

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Lck Inhibitor 25

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