| Cat. No. |
Product Name |
Information |
| PC-61101 |
JVW-1009
Sigma receptor ligand
|
A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively. |
| PC-61100 |
SAS-0132
Sigma 2 Receptor ligand
|
SAS-0132 (SAS132) is a novel potent, subtype-selective, brain penetrant sigma 2 receptor/PGRMC1 ligand with Ki of 90 nM, 9-fold selectivity over sigma 1 receptors. |
| PC-60790 |
PD144418
Sigma 1 inhibitor
|
PD144418 is a potent, selective sigma 1 ligand with Ki of 0.08 nM, >3000-fold selectivity over sigma 2 (Ki=1377 nM). |
| PC-60750 |
CM764
Sigma 2 receptor agonist
|
CM764 is a potent, selective sigma-2 receptor agonist with Ki of 3.5 nM, 25-fold selectivity over sigma-1 receptors (Ki=86.6 nM). |
| PC-60749 |
SN79
Sigma receptor antagonist
|
SN79 is a potent, orally active sigma receptor antagonist with Ki of 27 and 7 nM for σ1 and σ2, respectively. |
| PC-60748 |
CB-64D
Sigma 2 receptor agonist
|
CB-64D is a potent, selective sigma-2 receptor agonist with Ki of 16.5 nM, 200-fold selectivity over sigma 1 (Ki=3063 nM). |
| PC-60747 |
CM572
Sigma 2 receptor agonist
|
CM572 is a potent, selective, irreversible sigma-2 receptor partial agonist with Ki of 14.6 nM, >700-fold selectivity over sigma-1 receptors. |
| PC-60346 |
PB28 dihydrochloride
Sigma 2 receptor agonist, Sigma 1 inhibitor
|
PB28 dihydrochloride is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
| PC-60345 |
PB28
Sigma 2 receptor agonist, Sigma 1 inhibitor
|
PB 28 is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
| PC-60289 |
NE-100 hydrochloride
Sigma 1 receptor antagonist
|
NE-100 hydrochloride is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60288 |
NE-100
Sigma 1 receptor antagonist
|
NE-100 is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60076 |
IPAG
Sigma 1 inhibitor
|
IPAG is a prototypic selective inhibitor of sigma1 receptor that engages the unfolded protein response and induces autophagy in cancer cells. |
