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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-JVW-1009
JVW-1009

Chemical Structure : JVW-1009

CAS No.: 2089059-30-1

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JVW-1009 (JVW 1009;JVW1009)

货号: PC-61101Not For Human Use, Lab Use Only.

A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JVW-1009 is a small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively.
JVW-1009 reduces neurodegeneration in C. elegans model of amyloid precursor protein-mediated neurodegeneration.

物理化学性质&存储条件

分子量 340.47
分子式 C24H24N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,5R)-2-benzyl-N-phenyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[c]azepin-8-amine

参考文献

1. Yi B, et al. J Neurochem. 2017 Feb;140(4):561-575.

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