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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-MIN-101
MIN-101

Chemical Structure : MIN-101

CAS No.: 359625-79-9

MIN-101 (Roluperidone;CYR-101;MT-210;MIN101)

货号: PC-61105Not For Human Use, Lab Use Only.

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist with Ki of 7.53 nM and 8.19 nM respectively.
MIN-101 (Roluperidone, CYR-101, MT-210) shows  with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.

物理化学性质&存储条件

分子量 366.429
分子式 C22H23F2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[[1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro-1H-isoindol-1-one

参考文献

1. Davidson M, et al. Am J Psychiatry. 2017 Dec 1;174(12):1195-1202.

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