UKH-1114 |CAS:2113664-14-3 Probechem Biochemicals

Chemical Structure : UKH-1114

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UKH-1114 (UKH 1114;UKH1114)

货号: PC-61104Not For Human Use, Lab Use Only.

UKH-1114 (UKH1114) is a potent, sigma 2 receptor/Tmem97 agonist with Ki of 46 nM.

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生物&药学活性

UKH-1114 (UKH1114) is a potent, selective sigma 2 receptor/Tmem97 agonist with Ki of 46 nM.
UKH-1114 displays high selectivity for σ2R/Tmem97 versus >50 other proteins, including 5-HT receptors.
UKH-1114 relieves spared nerve injury-induced mechanical hypersensitivity without producing any motor impairment.

物理化学性质&存储条件

分子量	75.435
分子式	C22H24F3NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(9-(4-(trifluoromethyl)phenyl)-3,4,5,6-tetrahydro-1,6-methanobenzo[c]azocin-2(1H)-yl)propan-1-ol

参考文献

1. Sahn JJ, et al. ACS Chem Neurosci. 2017 Aug 16;8(8):1801-1811.

UKH-1114 (UKH 1114;UKH1114)

生物&药学活性

物理化学性质&存储条件

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UKH-1114 (UKH 1114;UKH1114)

生物&药学活性

物理化学性质&存储条件

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