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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-SAS-1121
SAS-1121

Chemical Structure : SAS-1121

CAS No.: 2095551-67-8

SAS-1121 (SAS 1121, SAS1121)

货号: PC-61103Not For Human Use, Lab Use Only.

SAS-1121 is a novel potent, subtype-selective sigma 2 receptor/PGRMC1 ligand with Ki of 16.2 nM, 574-fold selectivity over sigma 1 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SAS-1121 is a novel potent, subtype-selective sigma 2 receptor/PGRMC1 ligand with Ki of 16.2 nM, 574-fold selectivity over sigma 1 receptors.

    物理化学性质&存储条件

    分子量 477.605
    分子式 C28H35N3O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    benzyl (1R,5S)-8-(4-(3-ethoxy-3-oxopropyl)piperazin-1-yl)-1,3,4,5-tetrahydro-2H-1,5-methanobenzo[c]azepine-2-carboxylate

    参考文献

    1. Sahn JJ, et al. ChemMedChem. 2016 Mar 17;11(6):556-61.

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