| Cat. No. |
Product Name |
Information |
| PC-26027 |
VPC285785
SARS-CoV-2 Mpro inhibitor
|
VPC285785 is a novel covalent inhibitor of the SARS-CoV-2 main protease (Mpro) with IC50 of 0.8 uM, VPC285786 additionally inhibits human cathepsin Lwith IC50 of 4.2 uM. |
| PC-25957 |
4'-Fluorouridine
Antiviral agent
|
4'-Fluorouridine (4'-FlU, EIDD-2749) is a a broad-spectrum orally efficacious ribonucleoside analog that inhibits RSV, SARS-CoV-2 and related RNA viruses, targets RSV and SARS-CoV-2 RdRP causes sequence-modulated transcriptional stalling. |
| PC-25870 |
IMB-9C
HR1/HR2 inhibitor
|
IMB-9C is a specific small molecule inhibitor of heptad repeat 1/heptad repeat 2 (HR1/HR2) interaction, inhibits SARS-CoV-2-S-mediated cell-cell fusion. |
| PC-25844 |
CNiBuC
SARS-CoV-2 RdRp inhibitor
|
CNiBuC is the 5′-isobutyril ester prodrug of 1'-cyanocytidine and a reversible, competitive inhibitor of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), shows anti-SARS-CoV-2 activity with EC50 of 3.6 uM in Vero cells. |
| PC-25823 |
Avoralstat
Plasma kallikrein inhibitor, TMPRSS2 inhibitor
|
Avoralstat (BCX4161) is a potent and orally active plasma kallikrein inhibitor, also is a potent, selective Transmembrane protease, serine 2 (TMPRSS2) inhibitor (IC50=2.73 nM). |
| PC-25814 |
DY-III-281
SARS-CoV entry inhibitor
|
DY-III-281 is a SARS-CoV-2 small-molecule entry inhibitor with IC50 of 0.62 uM and 0.44 uM for SARS-CoV-1-S and SARS-CoV-2-S pseudoviruses. |
| PC-25730 |
H135
SARS-CoV-2 Mpro inhibitor
|
H35 is a potent and selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 12.7 nM, exerts broad anti-SARS-CoV-2 activity. |
| PC-25647 |
SARS-CoV-2 NSP14 inhibitor C10
SARS-CoV-2 NSP14 inhibitor
|
SARS-CoV-2 NSP14 inhibitor C10 is a potent, selective non-nucleoside inhibitor of SARS-CoV-2 nonstructural protein 14 (NSP14) with IC50 of 0.34 uM, exhibits potent antiviral activity and reverses NSP14-driven host modulation. |
| PC-25609 |
Licoflavone C
SARS-CoV-2 nsp13 inhibitor
|
Licoflavone C is a prenyl-flavone extracted from Genista ephedroides and SARS-CoV-2 nsp13 inhibitor, block both SARS-CoV-2 nps13 unwinding and ATPase activities with IC50 of 1.34 uM and 24.6 uM respectively. |
| PC-25564 |
SARS-CoV-2 Mpro inhibitor H102
SARS-CoV-2 Mpro inhibitor
|
SARS-CoV-2 Mpro inhibitor H102 is a potent covalent inhibitor of SARS-CoV-2 Mpro with IC50 of 8.8 nM. |
| PC-25310 |
SARS-CoV-2 Mpro inhibitor 18
Mpro inhibitor
|
SARS-CoV-2 Mpro inhibitor 18 is potent, reversible covalent inhibitor of SARS-CoV-2 Mpro with IC50 of 8 nM, inhibits virus induced cytopathic effect (CPE) with EC50 of 58 nM. |
| PC-25261 |
DNDI-6510
SARS-CoV-2 Mpro inhibitor
|
DNDI-6510 ((S)-x38) is a non-covalent, potent SARS-CoV-2, isoquinoline-based MPro inhibitor with IC50 of 40 nM, SARS-CoV-2 EC50 of 0.17 uM (A549 cells). |
