| Cat. No. |
Product Name |
Information |
| PC-23503 |
AB-343
SARS-CoV-2 Mpro inhibitor
|
AB-343 is a potent, selective, reversible covalent inhibitor of SARS-CoV-2 Mpro with Ki/IC50 of 2.8/8 nM, inhibits SARS-CoV-2 in Vero E6 cells and SARS-CoV-2-infected human lung cells (hACE2-A549) with EC50 of 18 nM. |
| PC-23483 |
TMPRSS2 inhibitor BC-11 hydrobromide
TMPRSS2 inhibitor
|
TMPRSS2 inhibitor BC-11 hydrobromide is a specific, covalent transmembrane protease serine 2 (TMPRSS2) inhibitor with IC50 of 1.44 uM in vitro TMPRSS2 enzymatic assay. |
| PC-23384 |
Jun12682
SARS-CoV-2 PLpro inhibitor
|
Jun12682 is a potent SARS-CoV-2 papain-like protease (PLpro) inhibitor with Ki/IC50 values of 37.7/106.8 nM. |
| PC-23375 |
NZ-804
SARS-CoV-2 Mpro inhibitor
|
NZ-804 is a potent, selective, non-peptidic, non-covalent inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 9 nM and antiviral EC50 of 14 nM. |
| PC-23359 |
ATV014
SARS-CoV-2 RdRp inhibitor
|
ATV014 (SHEN26) is a potent, orally active anti-SARS-CoV-2 nucleoside compound with EC50 of 0.48 uM against SARS-CoV-2 replicon, inhibits SARS-CoV-2 RdRp. |
| PC-23213 |
TL1228
GRP78 inhibitor
|
TL1228 is a small molecule inhibitor of SARS-CoV-2 and its target cells, blocking the recognition of the GRP78 cellular receptor by the viral Spike protein, also is a selective inhibitor of the dihydrofolate reductase (DHFR) type B1. |
| PC-22984 |
PF-07957472
SARS-CoV-2 PLpro inhibitor
|
PF-07957472 is a potent, selective, and orally available SARS-CoV-2 papain-like protease (PLpro) inhibitor with Ki of 2 nM, exhibits cell antiviral potency in Vero E6 cells with EC50 of 147 nM. |
| PC-22983 |
P23E02
Nsp1-SL1 inhibitor
|
P23E02 is a small molecule inhibitor of SARS-CoV-2 viral protein Nsp1-40S ribosomal subunit (stem-loop 1, SL1) interaction with IC50 of 2.26 uM, exhibits antiviral efficacy against various sarbecoviruses. |
| PC-22947 |
AVI-4206
SARS-CoV-2 Mac1 inhibitor
|
AVI-4206 is a potent, specific small molecule inhibitor of SARS-CoV-2 ADP-ribosylhydrolase macrodomain (Mac1) with IC50 of 20 nM in HTRF assays. |
| PC-22709 |
GST-HG171
SARS-CoV-2 3CLPro inhibitor
|
GST-HG171 (Atilotrelvir) is a potent, broad-spectrum, orally bioavailable small-molecule 3C-like (3CL) protease inhibitor, has broad-spectrum activity against different variants of SARS-CoV-2. |
| PC-22611 |
SIMM-036
SARS-CoV-2 PLpro inhibitor
|
SIMM-036 is a specific small molecule SARS-CoV-1 PLpro inhibitor with IC50 of 192.3 nM, inhibits the K63-deubiquitinase activity of SARS-CoV-2 Plpro. |
| PC-22547 |
Virapinib
Macropinocytosis inhibitor
|
Virapinib is a specific inhibitor of macropinocytosis with antiviral activity, limits viral entry by macropinocytosis for several viruses including SARS-CoV-2. |
