Chemical Structure : ML300
货号: PC-72197Not For Human Use, Lab Use Only.
ML300 (ML 300) is a potent, selective, noncovalent inhibitor of the SARS-CoV 3CL protease (3CLpro) with IC50 of 4.11 uM, inhibits SARS-CoV-2 3CLpro with IC50 of 4.99 uM.
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ML300 (ML 300) is a potent, selective, noncovalent inhibitor of the SARS-CoV 3CL protease (3CLpro) with IC50 of 4.11 uM, inhibits SARS-CoV-2 3CLpro with IC50 of 4.99 uM.
分子量 | 431.514 | |
分子式 | C23H21N5O2S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Han SH, et al. J Med Chem. 2021 Aug 4:acs.jmedchem.1c00598.
2. Turlington M, et al. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6172-7.
3. Turlington M, et al. 2012 Apr 9 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet].
4. Sang Hoon Han, et al. J Med Chem. 2021 Aug 4;acs.jmedchem.1c00598.
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