NSC 621601 | SARS-CoV-2 entry inhibitor | Probechem Biochemicals

Chemical Structure : NSC 621601

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NSC 621601 (Compound Q34)

货号: PC-72328Not For Human Use, Lab Use Only.

NSC 621601 (Compound Q34) is a potent, specific inhibitor of SARS-CoV-2 cellular entry with IC50 of 15 uM.

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生物&药学活性

NSC 621601 (Compound Q34) is a potent, specific inhibitor of SARS-CoV-2 cellular entry with IC50 of 15 uM.
Compound Q34 inhibits cellular entry of virus mediated by the SARS-CoV-2 spike protein specifically, but not by the VSV-G glycoprotein.
Compound Q34 inhibits SARS-CoV-2 cellular entry with a broad safety dose range.
Compound Q34 inhibits infection of SARS-CoV-2 pseudovirus in a dose-dependent manner and exhibits no cytotoxicity in a broad dose range.
Compound Q34 inhibits authentic SARS-CoV-2 infection of hACE2-HEK cells.
Compound Q34 inhibits authentic SAR-CoV-2 infection of human iPSC-derived neurons and astrocytes, and human lung cells.

物理化学性质&存储条件

分子量	354.454
分子式	C20H26N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N'-bis(phenylalanyl)ethane-1,2-diamine

参考文献

1. Qi Cui, et al. iScience. 2022 Jan 21;25(1):103684.

NSC 621601 (Compound Q34)

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物理化学性质&存储条件

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NSC 621601 (Compound Q34)

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物理化学性质&存储条件

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