| Cat. No. |
Product Name |
Information |
| PC-26442 |
MR1-114
SARS-CoV-2 PLpro inhibitor
|
MR1-114 is a potent, noncovalent SARS-CoV-2 papain-like protease (PLpro) inhibitor with enzyme IC50 of 37 nM. |
| PC-26441 |
PLpro inhibitor compound 7
SARS-CoV-2 PLpro inhibitor
|
PLpro inhibitor compound 7 is a potent, selective and covalent SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 94 nM and EC50 of 1.1 uM in SARS-CoV-2-infected Vero E6 cells |
| PC-26440 |
PLP_Snyder530
SARS-CoV-2 PLpro inhibitor
|
PLP_Snyder530 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 6.4 uM. |
| PC-26439 |
XR8-89
SARS-CoV-2 PLpro inhibitor
|
XR8-89 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 0.1 uM. |
| PC-26183 |
AVI-6451
SARS-CoV-2 Mac1 inhibitor
|
AVI-6451 is a potent and selective inhibitor of SARS-CoV-2 ADP-ribosylhydrolase Mac1 with IC50 of 28 nM, ITC Kd of 55 nM. |
| PC-26178 |
GK730
SARS-CoV-2 Mpro inhibitor
|
GK730 is a highly potent, specific SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 5.75 nM, weakly inhibits cathepsin L and does not inhibit cathepsin B. |
| PC-26050 |
EGT710
SARS-CoV-2 Mpro inhibitor
|
EGT710 (NVP-EGT710) is a potent, selective and oral nonpeptidomimetic reversible covalent SARS-CoV-2 Mpro inhibitor with IC50 of 7 nM, shows cellular potency with IC50 of 11 nM in CPE assay in Vero E6 cells. |
| PC-26027 |
VPC285785
SARS-CoV-2 Mpro inhibitor
|
VPC285785 is a novel covalent inhibitor of the SARS-CoV-2 main protease (Mpro) with IC50 of 0.8 uM, VPC285786 additionally inhibits human cathepsin Lwith IC50 of 4.2 uM. |
| PC-25870 |
IMB-9C
HR1/HR2 inhibitor
|
IMB-9C is a specific small molecule inhibitor of heptad repeat 1/heptad repeat 2 (HR1/HR2) interaction, inhibits SARS-CoV-2-S-mediated cell-cell fusion. |
| PC-25844 |
CNiBuC
SARS-CoV-2 RdRp inhibitor
|
CNiBuC is the 5′-isobutyril ester prodrug of 1'-cyanocytidine and a reversible, competitive inhibitor of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), shows anti-SARS-CoV-2 activity with EC50 of 3.6 uM in Vero cells. |
| PC-25730 |
H135
SARS-CoV-2 Mpro inhibitor
|
H35 is a potent and selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 12.7 nM, exerts broad anti-SARS-CoV-2 activity. |
| PC-25609 |
Licoflavone C
SARS-CoV-2 nsp13 inhibitor
|
Licoflavone C is a prenyl-flavone extracted from Genista ephedroides and SARS-CoV-2 nsp13 inhibitor, block both SARS-CoV-2 nps13 unwinding and ATPase activities with IC50 of 1.34 uM and 24.6 uM respectively. |
