XR8-24

Chemical Structure : XR8-24

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货号: PC-26443Not For Human Use, Lab Use Only.

XR8-24 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 0.56 uM and binding KD of 0.37 uM.

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XR8-24 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 0.56 uM and binding KD of 0.37 uM.

分子量	474.67
分子式	C28H34N4OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5-(azetidin-3-ylamino)-2-methyl-N-(1-(3-(5-(pyrrolidin-1-ylmethyl)thiophen-2-yl)phenyl)ethyl)benzamide

1. Zhengnan Shen, et al. J Med Chem. 2022 Feb 24;65(4):2940-2955.