PLpro inhibitor compound 7

Chemical Structure : PLpro inhibitor compound 7

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货号: PC-26441Not For Human Use, Lab Use Only.

PLpro inhibitor compound 7 is a potent, selective and covalent SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 94 nM and EC50 of 1.1 uM in SARS-CoV-2-infected Vero E6 cells

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

PLpro inhibitor compound 7 is a potent, selective and covalent SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 94 nM and EC50 of 1.1 uM in SARS-CoV-2-infected Vero E6 cells

物理化学性质&存储条件

分子量	488.54
分子式	C27H28N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (R,E)-4-(2-(3-(4-amino-2-((1-(naphthalen-1-yl)ethyl)carbamoyl)phenyl)propanoyl)hydrazineyl)-4-oxobut-2-enoate

参考文献

1. Sanders BC, et al. Nat Commun. 2023 Mar 28;14(1):1733.