AVI-6451 | SARS-CoV-2 Mac1 inhibitor | Probechem Biochemicals

Chemical Structure : AVI-6451

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货号: PC-26183Not For Human Use, Lab Use Only.

AVI-6451 is a potent and selective inhibitor of SARS-CoV-2 ADP-ribosylhydrolase Mac1 with IC50 of 28 nM, ITC Kd of 55 nM.

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AVI-6451 is a potent and selective inhibitor of SARS-CoV-2 ADP-ribosylhydrolase Mac1 with IC50 of 28 nM, ITC Kd of 55 nM.

分子量	355.37
分子式	C18H18FN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((8-cyclopropyl-6-fluoro-9H-pyrimido[4,5-b]indol-4-yl)amino)-4,4-dimethyloxazolidin-2-one

1. Jaishankar P, et al. J Med Chem. 2026 Jan 8;69(1):553-573.