pan-Coronavirus fusion inhibitor EK1

Chemical Structure : pan-Coronavirus fusion inhibitor EK1

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货号: PC-26476Not For Human Use, Lab Use Only.

EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species, potently inhibits SARS-CoV-2, competitively binds to heptad repeat 1 in the spike protein, blocking the formation of the six-helix bundle (6-HB) between viral HR1 and HR2 regions required for viral-cellular membrane fusion.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	4331.99
分子式	C196H317N43O64S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ser-Leu-Asp-Gln-Ile-Asn-Val-Thr-Phe-Leu-Asp-Leu-Glu-Tyr-Glu-Met-Lys-Lys-Leu-Glu-Glu-Ala-Ile-Lys-Lys-Leu-Glu-Glu-Ser-Tyr-Ile-Asp-Leu-Lys-Glu-Leu

参考文献

1. Xiu R, et al. J Virol. 2026 Mar 30:e0007626.

2. Monteiro A, et al. Curr HIV Res. 2021;19(6):465-475.