MPI5 | SARA-CoV2 Mpro inhibitor | Probechem Biochemicals

Chemical Structure : MPI5

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MPI5 (MPro inhibitor MPI5)

货号: PC-72436Not For Human Use, Lab Use Only.

MPI8 is a highly potent SARS-CoV-2 main protease (MPro) inhibitor with IC50 of 33 nM, completely prevented the SARS-CoV-2-induced cytopathogenic effect in Vero E6 cells at 2.5-5 uM and A549 cells at 0.16-0.31 uM.

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生物&药学活性

MPI8 is a highly potent SARS-CoV-2 main protease (MPro) inhibitor with IC50 of 33 nM, completely prevented the SARS-CoV-2-induced cytopathogenic effect in Vero E6 cells at 2.5-5 uM and A549 cells at 0.16-0.31 uM.

物理化学性质&存储条件

分子量	542.677
分子式	C29H42N4O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	benzyl ((S)-1-(((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

参考文献

1. Ma XR, et al. ChemMedChem. 2022 Jan 5;17(1):e202100456.

2. Yang KS, et al. bioRxiv. 2020 Jul 28:2020.07.28.223784.

MPI5 (MPro inhibitor MPI5)

生物&药学活性

物理化学性质&存储条件

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MPI5 (MPro inhibitor MPI5)

生物&药学活性

物理化学性质&存储条件

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