MU-UNMC-1

Chemical Structure : MU-UNMC-1

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货号: PC-38236Not For Human Use, Lab Use Only.

MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells.

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生物&药学活性

MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells.
MU-UNMC-1 blocked the entry of pseudovirus particles expressing SARS-CoV-2 Spike glycoprotein.
MU-UNMC-1 effectively blocked the replication of rapidly transmitting variants of concern: South African variant B.1.351 Omicron (IC50=9.27 μM) and Scotland variant B.1.222 (IC50=2.64 μM).

物理化学性质&存储条件

分子量	366.362
分子式	C14H10N2O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-methyl-2-nitrodibenzo[d,g][1,6,2]dithiazocin-7(6H)-one 5,5,12-trioxide

参考文献

1. Arpan Acharya, et al. J Virol. 2021 Nov 23;95(24):e0143721.

MU-UNMC-1

生物&药学活性

物理化学性质&存储条件

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MU-UNMC-1

生物&药学活性

物理化学性质&存储条件

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